Placental Steroid Hormone Synthesis: Unique Features and Unanswered Questions1

Qualitative Spatial Reasoning with the ALCIRCC Family - First Results and Unanswered Questions1

SUMO and ubiquitin modifications during steroid hormone synthesis and function.

Steroid hormones control many aspects of animal physiology and behaviour. They are highly regulated, among other mechanisms, by post-translational modifications of the transcription factors involved in their synthesis and response. In the present review, we will focus on the influence of SUMO (small ubiquitin-related modifier) and ubiquitin modifications on the function of transcription factors...

Recognising placental steroid sulphatase deficiency

bad, with variable results in between. Amputation of a digit is sometimes thought to produce a quicker return to work for the patient than replantation, but this is not borne out by published results."' The outlook in the leg is less clear. Functional results are often poor if a leg is replanted. Nevertheless, filleting may produce useful soft tissue which may be used as a vascularised free tra...

Modulation of free corticotrophin-releasing hormone, adrenal and placental steroid hormone levels induced by mifepristone during pregnancy.

UNLABELLED Mifepristone is a progesterone receptor antagonist widely used in obstetrics. The aim of the study was to focus on free corticotrophin-releasing hormone (CRH) and also describe modulation of adrenal and placental steroid hormone concentrations induced by mifepristone. METHODS Twenty-six women were enrolled in the study. They received mifepristone for termination of pregnancy. Mater...

I-34: Steroid Hormone Signalling at the FetomaternalInterface

Background: Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation. However, HESCs also abundantly express androgen receptors (AR), yet the role of this member of the superfamily of ligand-dependent transcription factors in the decidual process remains poorly elucidated. Materials a...